Cyclobenzaprine: Side Effects, dosage, uses, and more
While its exact mechanism of action is unknown, Robaxin (learn about Robaxin) is believed to relieve discomfort through its sedative effects. Generic methocarbamol is around $6.25 for 30 tablets of the 500mg dose with a BuzzRx drug discount card. Brand name Robaxin is approximately $95 for 30 tablets of the 750mg dose with a BuzzRx savings card. Generic cyclobenzaprine may be under $0.50 for 30 tablets of the 10mg dose through the BuzzRx discount program. Also, methocarbamol and cyclobenzaprine are not recommended in pregnant women, elderly adults, and young children.
Hyperpyretic crisis seizures, and deaths have occurred in patients receiving cyclobenzaprine (or structurally similar tricyclic antidepressants) concomitantly with MAO inhibitor drugs. Yes, cyclobenzaprine can make you very sleepy and this side effect may get worse with higher doses. Drowsiness is the most commonly reported side effect in studies, occurring in up to 38% (38 out of 100) of people.
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However, in general, physicians will prescribe Flexeril dosages according to the guidelines below as provided by the Mayo Clinic. CYCLOBENZAPRINE (sye kloe BEN za preen) treats muscle spasms. It works by relaxing your muscles, which reduces muscle stiffness.
Usually, people won’t die from a cyclobenzaprine overdose. There are over 12,000 people in the U.S who will go to the emergency room looking to be treated for Flexeril overdose. A study showed that 209 people who overdosed on Flexeril on its own survived the ordeal. Mixing the drug with other substances, however, has shown to cause accidents leading to death. If you experience withdrawal symptoms when not using cyclobenzaprine, or as the drug wears off, this could be a clear indication that you are addicted to Flexeril. If any of these indicators are familiar to you, it may mean you need to seek addiction treatment for your substance use.
Methocarbamol can be used for long or short-term treatment as advised by a doctor. On the other hand, cyclobenzaprine is generally not prescribed for longer than two or three weeks. Cyclobenzaprine—fully called cyclobenzaprine hydrochloride, orC20H22ClN—was first synthesized in 1961 by the pharmaceutical company Merck & Company. It is chemically related to tricyclic antidepressants, an early form of antidepressants invented in the 1950s. Within the last five years, emergency room department visits related to muscle relaxant abuse almost doubled; they increased from 15,830 to 31,763 visits.
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- The extended-release formulation should be administered at the same time each day.
Its actions on the CNS may also cause some of this medicine’s side effects. Cyclobenzaprine is a prescription drug used short-term to treat muscle spasms. In case of acute cyclobenzaprine overdose, emergency medicine physicians and triage nurses should stabilize the patient. If EKG demonstrates QRS prolongation, zanaflex compared to flexeril the clinician should initiate sodium bicarbonate therapy. In severe overdose, ventricular arrhythmias and seizures may require MICU-level of care under the supervision of a critical care physician. As discussed above, the clinician should consider contacting the poison control center in refractory cases.
Common symptoms of withdrawal
This medicine is available only with your doctor’s prescription. This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
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This may not be a complete list of all possible drug interactions. Consult a doctor with all the medications you may be taking. Flexeril is one of the most studied muscle relaxants; thus, it has more supporting evidence for its effectiveness. In a systematic review, it was found that, in general, muscle relaxants are comparable in effectiveness. This review included other muscle relaxants such as metaxalone, baclofen, tizanidine, orphenadrine, and chlorzoxazone. Robaxin or Flexeril are usually prescribed to treat musculoskeletal pain such as neck pain.
Other potential effects of overdosage include any of the symptoms listed under ADVERSE REACTIONS. The plasma concentration of cyclobenzaprine is increased in patients with hepatic impairment (see CLINICAL PHARMACOLOGY, Pharmacokinetics, Hepatic Impairment). Our Flexeril (cyclobenzaprine) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Your dose will depend on the severity of your pain and the formulation of cyclobenzaprine you’re using. The immediate-release tablets last for about four to six hours, while the extended-release tablets last around 24 hours. Avoid driving or hazardous activity until you know how this medicine will affect you. Ask your pharmacist any questions you have about refilling your prescription. Muscle relaxants should be avoided or monitored before operating machinery or driving a motor vehicle. Muscle relaxants like Robaxin or Flexeril can cause increased dizziness or drowsiness and impair cognitive performance.