Muscle Relaxers: Methocarbamol vs Cyclobenzaprine

Muscle Relaxers: Methocarbamol vs Cyclobenzaprine

If you don’t have insurance, you can use a SingleCare discount card to cut this cost to less than $8 depending on your pharmacy. Even if you do have insurance, it may be a good idea to find out if you can get a cheaper price on muscle relaxants. Those who are prescribed Robaxin tablets need to take two or three tablets four times per day, initially.

Generic forms may be sold under Amrix, an extended-release capsule, and Fexmid, an immediate-release capsule. The medication also works on the central nervous system and blocks nerve signals to the brain, which helps to relax muscles and prevent spasms. Common side effects include dizziness, drowsiness, dry mouth, and muscle weakness. Users are urged to follow all directions on their prescription label and know that their doctor could occasionally change their dose. Although some of the trials had treatment arms with other drugs, including diazepam,30-32,35,36 diflunisal (Dolobid),21 and methocarbamol,22 only cyclobenzaprine and placebo data from each trial were abstracted. Cyclobenzaprine was given in 10-mg tablets, except in 2 studies,18,21 in which 5-mg tablets were used.

Less commonly, patients are given a narcotic for the first few days of pain. To our knowledge, no studies have been done to determine the optimum combination of treatment modalities. Since many of these treatments may be operating on different aspects of back pain, there may be an additive effect. On the other hand, overmedication is a common problem among patients, and more may not be better. Studies to look at back pain management with a combination of common therapies are needed. Some clinicians, well versed with the sedative effects of cyclobenzaprine, prescribe it for the short term as a nighttime medicine.

If you or anyone you know is undergoing a severe health crisis, call a doctor or 911 immediately. Both of these drugs work similarly, which also means that most of the side effects of Flexeril vs. Baclofen are the same. Some side effects are unique to the specific drug and how it reacts in the patient’s body. In this blog post, we’ll explore some key differences between both medications to help you determine which option would offer better relief for your condition. Yes, one of the common side effects of Flexeril is drowsiness, which can make you feel sleepy or tired.


Cyclobenzaprine is a centrally acting skeletal muscle relaxant structurally related to tricyclic antidepressants. Cyclobenzaprine is a tricyclic amine salt that works in the central nervous system (CNS) as a depressant that reduces muscle hyperactivity. The recommended starting dose of Robaxin is six grams a day for the first 48 to 72 hours of treatment. Thereafter, the dosage can usually be reduced to approximately 4 grams a day. Robaxin may interact with pyridostigmine, donepezil, galantamine, rivastigmine, or tacrine. Tell your doctor all prescription and over-the-counter medications and supplements you use.

IBS Treatment Options and Prevention Strategies – Everyday Health

IBS Treatment Options and Prevention Strategies.

Posted: Tue, 26 Apr 2022 07:00:00 GMT [source]

Baclofen withdrawal can be life-threatening with possible multi-organ failure and psychological symptoms (2, 12). The study quality was assessed independently in duplicate, with substantial interrater agreement (κ, 0.79). Objective To perform a systematic review of cyclobenzaprine’s effectiveness in the treatment of back pain. Cyclobenzaprine is structurally and pharmacologically related to tricyclic antidepressants. Among the most dreaded toxicities linked with cyclical antidepressants, overdoses affect fast-acting sodium channels in the cardiac conduction system. Cyclical antidepressants block the cardiac sodium channel and cause prolongation of cardiac depolarization, which manifests as QRS widening on electrocardiograms.

Flexeril and Cyclobenzaprine: Misuse, Risks, and Addiction

Calls to our general hotline may be answered by private treatment providers. We may be paid a fee for marketing or advertising by organizations that can assist with treating people with substance use disorders. Because of the similarities between the two drugs, there’s often a question of which one between Flexeril vs. Baclofen is stronger. Abusing this drug increases the risk of anticholinergic toxidrome, as the acetylcholine builds up in the system due to the blockage of its receptors. It’s important to understand that using any medication for non-medical purposes, especially with the intention of achieving a high, can be dangerous and should be avoided.

  • Lioresal also will be the better option for the cases of multiple sclerosis, treating alcoholism and spinal cord issues.
  • On the other hand, cyclobenzaprine is generally not prescribed for longer than two or three weeks.
  • Any drug information published on regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.
  • Yes, one of the common side effects of Flexeril is drowsiness, which can make you feel sleepy or tired.

Comparison studies have not shown one skeletal muscle relaxant to be superior to another. Cyclobenzaprine is the most heavily studied and has been shown to be effective for various musculoskeletal conditions. The sedative properties of tizanidine and cyclobenzaprine may benefit patients with insomnia caused by severe muscle spasms. Methocarbamol and metaxalone are less sedating, although effectiveness evidence is limited. Adverse effects, particularly dizziness and drowsiness, are consistently reported with all skeletal muscle relaxants.

This medication can also negatively interact with alcohol and a host of other medications to produce annoying to serious side effects. If you do not drink or take other medications, this may not seem like a dire warning. This drug creates a physical dependency when people abuse it and over time, they may need it to sleep or even function normally. The “Cyclobenzaprine high” refers to the pleasurable and sometimes euphoric sensations that individuals might experience when misusing cyclobenzaprine, often for recreational purposes. The Diffucaps beads contained in each CER capsule are made by coating an inert core (such as sugar) with a layer of the active drug, cyclobenzaprine, and then by applying a seal coat and rate-controlling membrane.

You are encouraged to report negative side effects of prescription drugs to the FDA. It is intended for general informational purposes and is not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911. Since Robaxin and Flexeril have CNS depressant effects, they can interact with other drugs that have similar effects.